Total synthesis of 20(S) and 20(R)-camptothecin and compthotheci

Details Total synthesis of 20(S) and 20(R)-camptothecin and compthotheci Total synthesis of 20(S) and 20(R)-camptothecin and compthotheci

1990-04-17

1991-10-01

Rivers, Diana

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546 48, 546 92, C07D491147, C07D49122, A61K 3147

Patent

active

050535129

ABSTRACT:
The invention relates to a method of producing 20(S)-comptothecin, 20(R)-camptothecin and analogs thereof. The method involves the resolution of an mixture of enantiomers of an intermediate lactone.

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