Pyrazole and thiozole derivatives for treatment of gastrointesti

Details Pyrazole and thiozole derivatives for treatment of gastrointesti Pyrazole and thiozole derivatives for treatment of gastrointesti

1991-03-08

1993-06-29

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514406, 514407, 514926, 514927, A61K 31415, A61K 31425

Patent

active

052235211

ABSTRACT:
The invention relates to a method of preventing or treating gastrointestinal ulcer disease and microvascular injury in a mammal comprising administering to said mammal a pyrazole derivative alone or in combination with an ulcerogenic agent. The invention further relates to pharmaceutical compositions comprising a pyrazole derivative in combination with an ulcerogenic therapeutic agent to inhibit or prevent the ulcerogenic effect of that agent.

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