Molecular cloning and characterization of a gene sequence coding

Details Molecular cloning and characterization of a gene sequence coding Molecular cloning and characterization of a gene sequence coding

1990-07-06

1991-10-01

Moskowitz, Margaret

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

25 or more amino acid residues in defined sequence

530303, 530851, 530853, C07K 710

Patent

active

050534882

ABSTRACT:
Genes and DNA transfer vectors for the expression of human preprorelaxin; sub-units thereof, including genes and transfer vectors for expression of human prorelaxin and the individual A, B and C peptide chains thereof; and equivalents of all such genes. Method for synthesis of the peptides involving recombinant DNA techniques are provided.

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Maniatis et al. (1982) Molecular Cloning: A Laboratory Manual, Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y., pp. 190-199.
Sanger et al. (1977) Proc. Natl. Acad. Sci. U.S.A. 74, 5463-5467.
Marglin et al. (1970) Ann. Rev. Biochem. 39, 841-866.

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