Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1990-03-30
1991-10-01
Friedman, Stanley J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
A61K 3144
Patent
active
050534190
ABSTRACT:
A method of reducing death of CNS neurons in a human patient infected with a human immunodeficiency virus, involving administering to the patient a compound capable of reducing the gp120-responsive rise in free Ca.sup.++ ion concentration in the CNS neurons of the patient, in a concentration effective to cause such reduction.
REFERENCES:
Brenneman et al., 1988, Nature, 335:639.
Price et al., 1988, Science, 239:586.
Ho et al., 1989, Annals in Internal Medicine, 111:400.
Pomerantz et al., 1987, New Eng. J. Med., 317:1643.
Friedman Stanley J.
The Children's Medical Center Corporation
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