Method for the preparation of substituted and unsubstituted 2,3-

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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546321, 546168, 546171, 546176, C07D213803, C07D21516

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active

051226081

ABSTRACT:
There is provided a process for the preparation of a substituted or unsubstituted 2,3-pyridine or quinolinedicarboxylic acid by hydrolysis of a substituted or unsubstituted 2,3-pyridine or quinolinedicarboxylic acid diester with an acid having an ionization constant pK.sub.a of less than 3.0 followed by isolation of the product as the free acid or an acid salt.

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Hoogeweff et al., Chem. Ber., 13: 1639.
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Oakes et al., J. Chem. Soc., p. 4433 (1956).
Blank et al., J. Medicinal Chem., 17 (No. 10): 1065-(1974).

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