Process of making ketoalkanol esters of dihydrolysergic acid

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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546 67, 546 68, C07D45702

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active

047727098

ABSTRACT:
Ketoalkyl esters of 1-substituted-6-C.sub.1-4 straight chain alkyl (or allyl)ergoline-8.beta.-carboxylic acid, useful and 5HT receptor antagonists.

REFERENCES:
patent: 766362 (1985-08-01), Miser
patent: 3113133 (1963-12-01), Hofmann et al.
patent: 3183234 (1965-05-01), Garbrecht et al.
patent: 3228941 (1966-01-01), Bernardi et al.
patent: 3249617 (1966-05-01), Hofmann et al.
patent: 3580916 (1971-05-01), Garbrecht
patent: 4166182 (1979-08-01), Kornfeld et al.
patent: 4230859 (1980-10-01), Rucman
patent: 4246265 (1981-01-01), Kornfeld et al.
patent: 4284775 (1981-08-01), Temme
Berde, et al., Ergot Alkaloids and Related Compounds, Springer-Verlag, New York (1978) pp. 38-40, 45 and 46.
Fehr, et al. "Pemethylierung des Lysergsauregerusfes," Helv. Acta. vol. 53 (1970) pp. 2197-2201.
Organic Synthesis Coll. vol. I, 2nd. Ed. Wiley, New York, 201-202 (1946).
Elderfield et al., J. Org. Chem. 14, 605-637 (1949).
Nickon et al., J. Am Chem. Soc. 74, 5566-5570 (1952).
Robinson, Can. J. Chem. 32, 901-905 (1954).
Astill et al., J. Am. Chem. Soc. 77, 4079-4084 (1955).
Rapoport et al., J. Am. Chem. Soc. 89, 1942-1947 (1967).
Donetti et al., Tetrahedron Letters, No. 39, 3327-3328 (1969).
Cohen et al., J.P.E.T., 227, 327 (1983 (Cohen I).
Cohen et al., ibid 232, 770 (1984) (Cohen II).
Lemberger et al., Life Sci., 35, 71 (1984).
Cohen et al., Drug Dev. Res., 5, 313 (1985) (Cohen IV).
Hingten et al., Abstract 37.4, Soc. for Neurosci. (13th Annual Meeting, Nov., 1983).
U.S. Ser. No. 766,362 to Miser, filed Aug. 16, 1985.

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