Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1977-12-27
1979-04-03
Trousof, Natalie
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
2603322A, 546114, A61K 3144, C07D49504
Patent
active
041477871
ABSTRACT:
This invention relates to 4,5,6,7-tetrahydro-thieno[2,3-c]- and [3,2-c]-pyridines having the formulae: ##STR1## in which R.sup.1 is selected from hydrogen and halogen; R.sup.2 is selected from hydrogen and hydroxy; R.sup.3 and R.sup.4, which may be the same or different, are each selected from hydrogen, C.sub.1-6 alkyl, phenylalkyl having 1-6 carbon atoms in the alkyl moiety, and phenyl-C.sub.1-6 alkyl substituted on the phenyl nucleus with at least a substituent selected from halogen, C.sub.1-6 alkyl, C.sub.1-6 alkoxy, hydroxy, nitro, cyano and trifluoromethyl; and their acid addition salts.
Said derivatives possess therapeutically useful anti-sludge, anti-thrombosis and blood-platelet aggregation inhibiting properties.
REFERENCES:
patent: 3823151 (1974-07-01), Eichenberger et al.
patent: 3997545 (1976-12-01), Kuwada et al.
patent: 4065460 (1977-12-01), Heymes et al.
House, H., Modern Synthetic Reactions, 2nd Edition, W. A. Benjamin, Inc., Menlo Park, Cal., 1972, p. 656.
Parcor
Schwartz Richard A.
Trousof Natalie
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