Preparation of substituted lactams

Details Preparation of substituted lactams Preparation of substituted lactams

1988-06-02

1989-10-17

Schwartz, Richard A.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548551, C07D21176, C07D20726

Patent

active

048748650

ABSTRACT:
Preparation of substituted lactams Ia to Ic ##STR1## where n is 0 or 1, X is --O--CO--R.sup.1, --O--SO.sub.2 --R.sup.1, --CO--R.sup.2, --CO--O--R.sup.3 or --CO--NR.sup.4 R.sup.5, R.sup.1 is a C.sub.1 -C.sub.8 -radical of a carboxylic or sulfonic acid, R.sup.2 is C.sub.1 -C.sub.8 -alkyl, R.sup.3 is H or alkyl, aryl or aralkyl of not more than 8 carbon atoms, R.sup.4 and R.sup.5 are each H or C.sub.1 -C.sub.4 -alkyl or together form a 5-membered or 6-membered ring, by reacting a lactam II ##STR2## with a vinyl compound III

REFERENCES:
patent: 3332938 (1967-07-01), Mayhew et al.
patent: 3959356 (1976-05-01), Metcalf et al.
patent: 4235778 (1980-11-01), Gittos et al.
March, J., Advanced Organic Chemistry, McGraw Hill, New York, 1968, pp. 309, 753-754, 756 and 757.
G. I. Nikishin et al., Bulletin of the Academy of Sciences, USSR, Div. of Chem. Science, 1964, pp. 1745-1748.

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