Method of preparing sterile essentially amorphous cefazolin for

Details Method of preparing sterile essentially amorphous cefazolin for Method of preparing sterile essentially amorphous cefazolin for

1976-01-19

1977-01-11

Meyers, Albert T.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

A61K 3154

Patent

active

040027481

ABSTRACT:
Sterile, essentially amorphous cefazolin sodium for parenteral administration, having an improved solubility on reconstitution, is prepared by a freeze-drying process wherein a sterile solution of from about 10 to about 25 percent (W/V) of cefazolin sodium is exposed to an environment wherein the temperature is held at from about minus 50.degree. C. to minus 55.degree. C. until the temperature of the solution (frozen) is reduced to minus 48.degree. C. to minus 55.degree. C. before subjecting said frozen solution to a high vacuum and a moderate amount of heat to sublime the water therefrom.

REFERENCES:
patent: 3303193 (1967-02-01), Godfrey
patent: 3335136 (1967-08-01), Flynn
The Merck Index, 8th Edition, p. 222, (1968).

Affiliated with

Also associated with

Rating

Method of preparing sterile essentially amorphous cefazolin for does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of preparing sterile essentially amorphous cefazolin for , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of preparing sterile essentially amorphous cefazolin for will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1743905