Substituted-6H,8H-pyrimido-[1,2,3-cd]purine-8,10-(9H)-diones and

Details Substituted-6H,8H-pyrimido-[1,2,3-cd]purine-8,10-(9H)-diones and Substituted-6H,8H-pyrimido-[1,2,3-cd]purine-8,10-(9H)-diones and

1988-04-15

1990-02-27

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514267, 544115, 544251, A61K 31505, C07D48716

Patent

active

049046586

ABSTRACT:
Substituted-6H,8H-pyrimido[1,2,3-cd]purine-8,10(9H)-diones and substituted-6H,10H-pyrimido[1,2-cd]purin-10-ones which are useful as cognition enhancing agents, anxiolytic agents and/or antihypertensive agents in the treatment of cognitive and relative neutral behavioral problems, anxiety and hypertension in mammals.

REFERENCES:
patent: 4236005 (1980-11-01), Dusza et al.
patent: 4663326 (1987-05-01), Hamilton
patent: 4680295 (1987-07-01), Fowler et al.
Leonard et al., Chemical Abstracts, vol. 65:17264g, (1966).
Seden et al., Chemical Abstracts, vol. 84:59392s, (1976).
Holy, Chemical Abstracts, vol. 96:181605b, (1982), also attached subjects Index page.
Kim et al., Chemical Abstracts, vol. 109:128973f, (1988), see attached CAS ONLINE search pages.
Crook et al., ed., "Assessment in Geriatric Psychopharmacology", Mark Powley Associates, Inc., (1983), pp. 263-269.

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