Process for the production of 4-aminobutyramide hydrochloride

Details Process for the production of 4-aminobutyramide hydrochloride Process for the production of 4-aminobutyramide hydrochloride

1981-11-16

1983-03-08

Waltz, Thomas A.

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

C07C103183

Patent

active

043762158

ABSTRACT:
4-aminobutyramide hydrochloride is produced by saponifying 4-(benzylamino)-or-4-(dibenzylamino)-butyronitrile to the corresponding substituted 4-aminobutyramide and subjecting this in the form of the hydrochloride in the presence of an inert solvent and a platinum metal catalyst to a hydrogenation treatment whereby the benzyl group or the two benzyl groups are split off.

REFERENCES:
patent: 3573304 (1971-03-01), Eberle et al.
patent: 4322552 (1982-03-01), Kleemann et al.
Wagner et al., Synthetic Organic Chemistry, John Wiley & Sons, N.Y., N.Y., 1953, p. 570.
Farquharson et al., CA 55:23522c (1952).

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