Process for 6-(aminomethyl)penicillanic acid 1,1-dioxide and der

Details Process for 6-(aminomethyl)penicillanic acid 1,1-dioxide and der Process for 6-(aminomethyl)penicillanic acid 1,1-dioxide and der

1983-06-06

1985-03-05

Rizzo, Nicholas S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602452T, 2602391, C07D49900, A61K 31425

Patent

active

045029903

ABSTRACT:
A process for the preparation of beta-lactamase inhibiting 6-alpha-(aminomethyl)penicillanic acid 1,1-dioxide and derivatives. R- and S-1-(ethoxycarbonyloxy)ethyl 6-alpha-(aminomethyl)penicillanate 1,1-dioxide are specifically described.

REFERENCES:
patent: 4207323 (1980-06-01), Beattie et al.
patent: 4234579 (1980-11-01), Barth
patent: 4237051 (1980-12-01), McCombie
patent: 4287181 (1981-09-01), Kellogg
patent: 4309347 (1982-01-01), Bigham
DiNinno et al., J. Org. Chem., 42, pp. 2960-2965, (1977).

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