Optics: measuring and testing – For light transmission or absorption – By comparison
Patent
1979-12-26
1985-03-05
Rosenberger, R.
Optics: measuring and testing
For light transmission or absorption
By comparison
G01N 2100
Patent
active
045027862
ABSTRACT:
A method and apparatus for automatically determining the amount of a hemoglobin species in a blood sample in relation to the total amount of hemoglobin in a blood sample by simultaneously determining the relative concentrations of the two samples with a spectrophotometer. The spectrophotometer has two channels each of which is associated with one sample. Each channel determines the intensity of light from a light source which is transmitted through its sample and received by a photodetector. Thereafter, the apparatus calculates the relative concentration of the two samples (A.sub.1 /A.sub.2) or optionally the normalized concentration of the samples (A.sub.1 /A.sub.1 +A.sub.2). The apparatus includes automatic self-calibration to compensate for any degradation of the optical system.
REFERENCES:
patent: 3504978 (1970-04-01), Shibata et al.
patent: 3528749 (1970-09-01), Bowker
patent: 3678505 (1972-07-01), Mostyn
patent: 3684378 (1972-08-01), Lord
patent: 3810696 (1974-05-01), Hutchins
patent: 3970393 (1976-07-01), Krygeris et al.
patent: 4063817 (1977-12-01), Shimamura et al.
Golias Tipton L.
Mostyn, Jr. William T.
Helena Laboratories Corporation
Rosenberger R.
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