Process for producing 3,7-dihydroxytropolone and antitumor use t

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound

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435886, C12P 726, C12R 1465

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active

048330795

ABSTRACT:
The compound 3,7-dihydroxytropolone having the formula ##STR1## is produced by fermentation of Streptomyces tropolofaciens and is found to inhibit the growth of mammalian tumors.

REFERENCES:
Chem Abs 109(15) 122100X, Sugawara et al., Jour Antibiot 41(7)862-8 (1988).
Biotech Abs 88-10192, Sugawara et al., Jour Antibiot 41(7)862-8(1988).
Derwent Abs 84-227832/37 (J59134744)8-84.
Derwent Abs 84-227823/37 (J59134720)8-84.
Derwent Abs 790287 B/02 (J53/5954)11-1978.

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