Radiation compatible iodine formulation

Details Radiation compatible iodine formulation Radiation compatible iodine formulation

1988-09-19

1990-02-27

Robinson, Allen J.

Drug, bio-affecting and body treating compositions

Inorganic active ingredient containing

Elemental iodine or iodine compound

A61K 3336

Patent

active

049044800

ABSTRACT:
A germicidal iodine-containing composition includes iodine, an iodophor, cupric ions and nitrite ions in an aqueous base. Iodide ions which form in the composition during radiation sterilization or prolonged shelf life are oxidized back to iodine by the cupric ions in a Ph dependent reaction which consumes hydrogen ions formed concurrently with the iodide ions. Cuprous ions formed during the oxidation are spontaneously cycled back to cupric ions by traces of air present in the composition. The composition may include nitrite ions to augment the conversion of cuprous ions back to the cupric form.

REFERENCES:
patent: 4113857 (1978-09-01), Shetty
patent: 4576818 (1986-03-01), Shetty
patent: 4668510 (1987-05-01), Shetty

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