Process for the preparation of a D-(+)-biotin intermediate

Details Process for the preparation of a D-(+)-biotin intermediate Process for the preparation of a D-(+)-biotin intermediate

1992-03-05

1993-08-10

Higel, Floyd D.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

5483031, C07D49504, C07D49104, C07D33332, C07D47300

Patent

active

052350657

ABSTRACT:
The present invention relates to a process for the preparation of heterocyclic compounds which are suitable as intermediates for the preparation of D-(+)-biotin, and to a process for the preparation of D-(+)-biotin itself. The invention further relates to intermediates in this process.

REFERENCES:
patent: 3740350 (1973-06-01), Shanefield
patent: 3740416 (1973-06-01), Gerecke et al.
patent: 3876656 (1975-04-01), Aoki et al.
patent: 4636566 (1987-01-01), Holick et al.
patent: 4876350 (1989-10-01), McGarrity et al.
patent: 4877882 (1989-10-01), Poetsch et al.
Rawal et al., J. Org. Chem. vol. 55, pp. 5181 to 5183 (1990).
Isaka et al., Jap. Bull. Pharm. Chem, vol. 88(8), pp. 1068-1073 (1968).
Oyke, "The Chemistry of Vitamins", Chapter 9, pp. 161-181 (1965).

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