Combination chemotherapy

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...

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514171, 514553, 514597, A61K 3166, A61K 3156, A61K 31185, A61K 3117

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active

057671109

ABSTRACT:
Suramin in combination with a vinca alkaloid or estramustine is synergistic for treating cancer.

REFERENCES:
patent: 5158940 (1992-10-01), LaRocca et al.
patent: 5385936 (1995-01-01), Flack et al.
Studies of Suramin (Antrypol: Bayer 205), vol. 40, 1946, Dewey et al., pp. 119-124.
Journal of Clinical Oncology, vol. 7, No. 4, 1989, Stein et al., pp. 499-508.
Journal of the National Cancer Institute, vol. 86, No. 20, 1994, Chou et al., pp. 1517-1524.
Synergism and Antagonism in Chemotherapy, Chapter 6, 1991, Chou et al., pp. 223-241.
Journal of the National Cancer Institute, vol. 82, No. 14, 1990, Fruehauf et al., pp. 1206-1209.
Proceedings of the American Association for Cancer Research, vol. 35, 1994, Rago et al., p. 329, abstract 1956.
Molecular Pharmacology, vol. 33, No. 4, 1988, Zamora et al., pp. 454-462.
Carter et al, Chemotherapy of Lawler, 2nd ed, John Wiley & Sons, N.Y., N.Y., 1981 p. 126.

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