Ocular solution

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

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514 54, 514912, A61K 31715

Patent

active

057671052

ABSTRACT:
An ophthalmologic solution containing oligosaccharides in an appropriate concentration. The oligosaccharide preferably is a disaccharide such as sucrose, maltose or lactose. The disaccharide is placed in solution in a pharmacologically acceptable concentration ranging from 0.1% to 11.4%. The disaccharide can be added to physiologic saline, Lactated Ringers, balanced salt solution or other appropriate physiologic solution. The disaccharide does not enter the tissue cells and maintains an extracellular pressure gradient that prevents flow of fluid into the eye. The solution is used to replace vitreous or used topicall. One or more pharmacologic agents or drugs may be added to the solution.

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W. Keeton, Biological Science Second Edition, pp. 30-31, 42, 174-175 Intravitreal Surgery, Chapter 3, pp. 59-65, 104-105 (1979).
Jicst-Eplus 87015068o Abstract of Journal of Japanese Soc. Hospital Pharmacy (1986).
BioSis Abstract of Invest Ophamol Visual Science 27(11). 1986.

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