Piperidine derivative and pharmaceutical composition

Details Piperidine derivative and pharmaceutical composition Piperidine derivative and pharmaceutical composition

1986-12-24

1989-07-18

Hollrah, Glennon H.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514318, 514321, 544236, 544238, 544285, 546 99, 546142, 546176, 546192, 546193, 546197, 546230, 546233, 546234, 546194, 546204, 549451, 549468, A61K 31445, C07D21126

Patent

active

048494313

ABSTRACT:
A novel piperidine derivative or a pharmacologically acceptable salt thereof is used in the treatment and prevention of dementias and sequelae of cerebrovascular diseases. These compounds also exhibit strong, highly selective anticholinesterase activity and may be orally or parenterally administered.

REFERENCES:
patent: 4158060 (1979-06-01), Kaplan et al.
patent: 4360531 (1982-11-01), McMillan et al.
patent: 4559343 (1985-12-01), Storni
patent: 4604393 (1986-08-01), Cornu et al.
DeGraw, et al., "J. Med. Chem.", vol. 10, No. 2, 1967, pp. 174-177.

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