Therapeutic method of treating patients suffering from AIDS and

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...

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A61K 3135

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active

056312881

ABSTRACT:
A novel therapeutical utilization of L-carnitine, acyl L-carnitines and the pharmacologically acceptable salts thereof is disclosed, for treating immune and metabolic alterations in patients suffering from AIDS and AIDS-related syndromes and in asymptomatic HIV-seropositive patients.
The L-carnitine amount to be administered according to this novel use is about 6-8 grams daily, via the oral route or an equivalent amount of an acyl L-carnitine or a pharmacologically acceptable salt thereof, i.e. three-four times as much the dose usually administered for the already known therapeutic uses of L-carnitine.

REFERENCES:
patent: 4474812 (1984-10-01), Cavazza
patent: 4968719 (1990-11-01), Brevetti
De Simone et al, AIDS, vol. 6, pp. 203-205 (1992).
Douvos et al 1991, PNAS vol. 88 pp 6328-6332.
Bogden et al 1990, Ann NY Acad Sci #587 pp. 189-195.
Scandurra et al. 1990 113CA109301b.
Marata et al. 1985 102CA218208v.

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