Thiazole precursors for the preparation of biotin

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

546 19, 548110, 548146, C07D27710, C07D47110, C07D51310, C07D27760

Patent

active

046313451

ABSTRACT:
A novel process is described for preparation of biotin comprising preparation of substituted 3H, 5H-imidazo[1, 5c]tetrahydro thiazoles by contacting the boron triflouride adduct of an appropriate thiazoline with the metallic derivative of an ester enolate, reducing the ester, hydrolyzing the thiazolidine moiety and hydrolyzing or oxidizing the resultant compound. Intermediates obtained in the preparation of biotin by the above process and alternate procedures for preparing said intermediates are also presented. A novel process for preparation of d-biotin is also given.

REFERENCES:
patent: 2865924 (1958-12-01), Asinger et al.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Thiazole precursors for the preparation of biotin does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Thiazole precursors for the preparation of biotin, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Thiazole precursors for the preparation of biotin will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-172436

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.