Receptor selective analogues of cholecystokinin-8

Details Receptor selective analogues of cholecystokinin-8 Receptor selective analogues of cholecystokinin-8

1994-07-25

1997-05-20

Tsang, Cecilia J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

530328, A61K 3800, C07K 700, C07K 706

Patent

active

056312300

ABSTRACT:
Analogues of cholecystokinin-8, which are receptor selective, vary from the normal hormone by alteration of at least one of the two, three or six position amino acids of the natural sequence.

REFERENCES:
patent: 4400377 (1983-08-01), Zetler et al.
Hruby et al, Peptides, 1990, 707-709.
Durieux, et al, vol. 137, Biochemical and Biophysical Research Communication, pp. 1167-1173 (1986).
Sawyer, et al, Abstract, Neural Endocr. Pept. Recept. 5th (1986), pp. 541-552.
Wire et al, Proc. West. Pharmacol. Soc., 33, 65-68, (1990).
Knapp et al, Pharmacology and Experimental Therapeutics, vol. 255, No. 3, 1278-86. 1990.
Wire et al, Proc. West Pharmacol Soc. 34, 453-459 (1991).
Ayres, et al, Proc. West Pharmacol Soc. 34: 477-484, 1991.
Knapp et al, J. of Pharmacology, 191-98, 1991.

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