Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1988-10-06
1990-07-10
Hollrah, Glennon H.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
549214, 549292, 544 584, 544 59, 544 60, 544148, 544149, 544164, 544172, 544360, 544372, 544374, 544382, 544384, 546186, 546187, 546189, 546244, 546245, 548517, 548518, 548531, 548557, 548558, 560 35, 560 56, 560 59, 560 60, 560116, 560119, 562444, 562466, 562467, A61K 31335, C07D31500
Patent
active
049407279
ABSTRACT:
Novel 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors are useful as anti-hypercholesterolemic agents and are represented by the following general structural formulae (I) and (II): ##STR1##
REFERENCES:
patent: 4361515 (1982-11-01), Terahara et al.
patent: 4450171 (1984-05-01), Hoffman et al.
patent: 4661483 (1987-04-01), Hoffman et al.
patent: 4668699 (1987-05-01), Hoffman et al.
Halczenko Wasyl
Hartman George D.
Hensens Otto D.
Houck David R.
Inamine Edward S.
DiPrima Joseph F.
Hollrah Glennon H.
Merck & Co. , Inc.
Owens A. A.
Winokur Melvin
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