Cephem compounds

Details Cephem compounds Cephem compounds

1986-08-08

1990-07-10

Rizzo, Nicholas S.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

540221, C07D50157, A61K 31545

Patent

active

049407023

ABSTRACT:
.beta.-Lactam antibiotics are disclosed which have the formulae (Ia) or pharmaceutically acceptable salts or pharmaceutically acceptable in vivo hydrolysable esters thereof: ##STR1## wherein R.sup.1 is phenyl, substituted phenyl, cyclohexenyl, cyclohexadienyl, or an optionally substituted 5- or 6-membered heterocyclic ring containing up to three hetero-atoms selected from oxygen, sulphur or nitrogen; R.sup.2 is hydrogen or optionally substituted C.sub.1-6 alkyl; R.sup.3 is an optionally substituted 5- or 6- membered heterocyclic group containing one or two nitrogen heteroatoms; or R.sup.2 and R.sup.3 together with the nitrogen atom to which they are attached form an optionally substituted 5- or 6- membered heterocyclic group contaning one or two nitrogen heteroatoms; R.sup.4 is a substituted pyridinium group; and CO.sub.2 R is carboxy or a carboxylate anion; and also the use thereof.
Processes for the preparation of the compounds are disclosed together with intermediates for use therein.

REFERENCES:
patent: 4539149 (1985-09-01), Mulne
patent: 4555363 (1985-11-01), Mulne
patent: 4609652 (1986-09-01), Milner
patent: 4670431 (1987-06-01), Milner
patent: 4684639 (1987-08-01), Buoton et al.

Affiliated with

Also associated with

Rating

Cephem compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Cephem compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cephem compounds will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1721004