Methods and apparatus for intraluminal deposition of hydrogels

Surgery – Instruments – Internal pressure applicator

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

604284, A61M 2900

Patent

active

061529435

ABSTRACT:
Methods and apparatus of forming hydrogel systems in situ are provided using a delivery system configured to deliver two or more fluent prepolymer solutions without premature crosslinking. The delivery system comprises separate first and second lumens coupling first and second inlet ports and first and second outlet ports, respectively, and may include a balloon, flexible distal region, mixing chamber or steerable distal end. Multi-component hydrogel systems suitable for use with the inventive methods and apparatus are also described.

REFERENCES:
patent: 3640741 (1972-02-01), Etes
patent: 3865108 (1975-02-01), Hartop
patent: 3991766 (1976-11-01), Schmitt et al.
patent: 3992562 (1976-11-01), Denzinger et al.
patent: 4002173 (1977-01-01), Manning et al.
patent: 4014335 (1977-03-01), Arnold
patent: 4207893 (1980-06-01), Michaels
patent: 4369229 (1983-01-01), Shah
patent: 4655771 (1987-04-01), Wallsten
patent: 4741872 (1988-05-01), DeLuca et al.
patent: 4762129 (1988-08-01), Bonzel
patent: 4826945 (1989-05-01), Cohn et al.
patent: 4938763 (1990-07-01), Dunn et al.
patent: 5067497 (1991-11-01), Greear et al.
patent: 5090995 (1992-02-01), Kubota et al.
patent: 5100992 (1992-03-01), Cohn et al.
patent: 5160745 (1992-11-01), DeLuca et al.
patent: 5171148 (1992-12-01), Wasserman et al.
patent: 5198220 (1993-03-01), Damani
patent: 5324775 (1994-06-01), Rhee et al.
patent: 5328471 (1994-07-01), Slepian
patent: 5410016 (1995-04-01), Hubbell et al.
patent: 5522898 (1996-06-01), Bao
patent: 5645583 (1997-07-01), Villain et al.
patent: 5785679 (1998-07-01), Abolfathi et al.
patent: 5830196 (1998-11-01), Kicks
patent: 5895405 (1999-04-01), Inderbitzen
Abusafieh, A. et al., "Development of Self-Anchoring Bone Implants. I. Processing and Material Characterization," J. Biomat. Mater. Res., (Appl. Biomater.), 38:314-327 (1997).
Bhatia, S. et al., "The Effect of Site of Implantation and Animal Age on Properties of Polydioxanone Pins," J. Biomater. Sci., Polymer. Edn., Bamford, C.H. et al., eds., 6(5): 435-446 (1994).
Brundin, J., "Hydrogel Tubal Blocking Device: P-Block," Female Transcervical Sterilization, Zatuchni, G.I. et al., eds., Harper & Row, Philadelphia, Pennsylvania, 240-244 (1982).
Chisholm, R.A. et al., "Fibrin Sealant as a Plug for the Post Liver Biopsy Needle Track," Clinical Radiology, 40(6):627-628 (1989).
Greenberg, A.R. et al., "Stimulation of Bone Formation by a Swelling Endosseous Implant," J. Biomed. Maters. Research, 12:929-933 (1978).
Handbook of Common Polymers, compiled by Roff, W.J. et al., CRC Press, Cleveland, Ohio.
Jarrett P.K. et al., "Bioabsorbable Hydrogel Tissue Barrier: In Situ Gelation Kinetics," Soc. for Biomater., Transactions of 21st Annual Meeting:182 (1995).
Medicinal Chemistry, 3rd Ed., Parts 1 and 2, Burger, A., ed., Wiley-Interscience.
Nagaoka, S. et al., "Interaction Between Blood Components and Hydrogels with Poly(oxyethylene) Chains," Polymers As Biomaterials, Shalaby, S.W. et al., eds., Plenum Press, New York, 361-374 (1984).
Okano, T. et al., "Effects of Hydrophilic and Hydrophobic Microdomains on Mode of Interaction Between Block Polymer and Blood Platelets," J. Biomed. Mats.. Research, 15:393-402 (1981).
Onishi, Y. et al., "Study of Dextran-Methyl Methacrylate Graft Copolymer," Contemporary Topics in Polymer Science, Bailey, W.J. et al., eds., Plenum Press, New York, 4:149-162 (1984).
Park, K., "Enzyme-Digestible Swelling Hydrogels as Platforms for Long-Term Oral Drug Delivery: Synthesis and Characterization," Biomaterials, 9:435-441 (1988).
Park, K. et al., Biodegradable Hydrogels for Drug Delivery, Technomic Publishing Co., Inc., Lancaster, Pennsylvania (1993).
Remington's Pharmaceutical Sciences, 14th Ed., J.E. Hoover et al., eds., Mack Publishing Co., Easton, Pennsylvania (1970).
Sawhney, A.S. et al., "Bioerodible Hydrogels Based on Photopolymerized Poly(ethylene glycol)-co-poly(.alpha.-hydroxy acid) Diacrylate Macromers," Macromolecules, 26:581-587 (1993).
Shah, K.R., "Novel Two-Phase Polymer System," Polymer, 28:1212-1216 (1987).
Shah, K.R., "Hydrophilic-Hydrophobic Domain Polymer Systems," Water Soluble Polymers, Chap. 30, Shalaby, S.W. et al., eds., Amer. Chem. Soc., Washington, D.C., 467-483 (1991).
Shalaby, S.W., "Bioabsorbable Polymers," Encyclopedia of Pharmaceutical Technology, Swarbrick, J. et al., eds., Marcel Dekker, Inc., New York, 1:465-476 (1988).
Shalaby, S.W. et al., "In Vitro and In Vivo Studies of Enzyme-Digestible Hydrogels for Oral Drug Delivery," J. Controlled Release, 19:131-144 (1992).
Silberberg, A., "Network Deformation in Flow," Molecular Basis of Polymer Networks, Baumgartner, A. et al., eds., Springer-Verlag, Berlin, 42:147-151 (1989).
Smith, K.L. et al., "Association Reactions for Poly(alkylene Oxides) and Polymeric Poly (carboxylic Acids)," Ind. Eng. Chem., 51(11):1361-1364 (1959).
The Drug, The Nurse, The Patient (Including Current Drug Handbook), Falconer's 7th Ed., W.B. Saunders Co., Philadelphia, Pennsylvania (1974).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Methods and apparatus for intraluminal deposition of hydrogels does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods and apparatus for intraluminal deposition of hydrogels, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods and apparatus for intraluminal deposition of hydrogels will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1719876

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.