Synthetic peptides having growth promoting activity

Details Synthetic peptides having growth promoting activity Synthetic peptides having growth promoting activity

1975-04-28

1977-11-15

Phillips, Delbert R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

195 17, 424177, C07C10352, A61K 3700, C12B 900

Patent

active

040585123

ABSTRACT:
Novel synthetic peptides of the general formula ##STR1## and the corresponding reduced, linear form. The cyclic form of the peptide is produced by oxidation of the corresponding linear compound thereby providing the divalent dithio group --S--S-- joining the beta carbon of each of the cysteine moieties. In the above formula X is serine (SER) or lysine (Lys), and Y is OH or Thr-Glu-Gly-Phe. The obtained synthetic peptides, in either form, are useful in promoting growth of cells of mammalian tissues.

REFERENCES:
patent: 3798203 (1974-03-01), Brugger et al.
patent: 3849388 (1974-11-01), Rittel et al.

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