Use of nitric oxide in the treatment of exercised induced pulmon

Details Use of nitric oxide in the treatment of exercised induced pulmon Use of nitric oxide in the treatment of exercised induced pulmon

1996-05-07

1998-06-16

Lewis, Aaron J.

Surgery

Respiratory method or device

12820312, 12820522, A61M 1500

Patent

active

057655480

ABSTRACT:
The administration of nitric oxide in controlled doses to horses during high intensity exercise is described. The nitric oxide is beneficial to prevent exercised induced pulmonary hemorrhaging by reducing pulmonary artery pressure with a concomitant compensating reduction in pulmonary vascular resistance. The nitric oxide is either administered to the equine through inhalation during exercise or via a stand alone nitric oxide gas source followed by an intramuscular injection of a nitric oxide augmenter prior to exercise.

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patent: 5536241 (1996-07-01), Zapol
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Pulmonary Artery Wedge Pressure Increases With High-Intensity Exercise In Horses; Murli Manobar, BVSc, PhD; pp. 142-146; Am J Vet Res, vol. 54 No. 1, Jan., 1993.
Stress Failure Of Pulmonary Capillaries in Racehorses With Exercise-Induced Pulmonary Hemorrhage; John B. West et al.; pp. 2-14; 1993 the American Physiological Society.
Ultrastructural Appearances Of Pulmonary Capillaries At High Transmural Pressures; Tsukimoto et al. pp. 4-13; 1991 American Physiological Society.
Fast Track Pulmonary Artery Pressure During Exercise In The Horse After Inhibition Of Nitric Oxide Synthase; Mills et al.; pp. 1-4; 1996 Bailliere Tindall.

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