Prosthetic disc containing therapeutic material

Details Prosthetic disc containing therapeutic material Prosthetic disc containing therapeutic material

1988-07-25

1990-02-27

Apley, Richard J.

Prosthesis (i.e., artificial body members), parts thereof, or ai

Implantable prosthesis

Bone

623 12, 6048911, 604131, 424424, 424DIG7, A61F 244, A61M 3100

Patent

active

049042602

ABSTRACT:
By implanting two prosthetic disc capsules side-by-side into a damaged disc of a human spine, both height and motion, including front-to-back bending, can be maintained. Each prosthetic disc capsule has a bladder enclosing a fluid containing a therapeutic material that is slowly diffusible through a semi-permeable membrane of the bladder. The fluid filling the semi-permeable membrane preferably is an aqueous solution that has gel-like properties that afford a viscosity and velocity-shear behavior imitating the natural rheology of intradiscal nuclear tissue. Those properties are obtained when the aqueous solution is of a mucopolysaccharide such as hyaluronic acid or soldium hyaluronate.

REFERENCES:
patent: 3855638 (1974-12-01), Pilliar
patent: 3934274 (1976-01-01), Hartley, Jr.
patent: 3948254 (1976-04-01), Zaffaroni
patent: 3987790 (1976-10-01), Eckenhoff et al.
patent: 4367741 (1983-01-01), Michaels
patent: 4485096 (1984-11-01), Bell
patent: 4772287 (1988-09-01), Ray et al.
Hawley's Condensed Chemical Dictionary, Eleventh Edition, Van Nostrand Reinhold Co., 1987, p. 610.

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