C.sub.1-4 alkanoylphenyl-esters of 5-hydroxy-PGI.sub.1, .DELTA..

Details C.sub.1-4 alkanoylphenyl-esters of 5-hydroxy-PGI.sub.1, .DELTA.. C.sub.1-4 alkanoylphenyl-esters of 5-hydroxy-PGI.sub.1, .DELTA..

1979-06-14

1980-09-02

Jiles, Henry R.

Harness for working animal

542429, 2603452, 26034622, C07D30793, C07D31194

Patent

active

042207584

ABSTRACT:
Acyl-substituted phenyl esters of prostacyclin-type compounds, for example the 4-acetylphenyl ester of prostacyclin (PGI.sub.2) illustrated by the formula ##STR1## and including esters of the isomeric 6-hydroxy-PGI.sub.1 and 6-keto-PGF.sub.1.alpha. compounds, said esters having pharmacological activity. Processes for preparing them and the appropriate intermediates are disclosed.

REFERENCES:
Johnson et al., Prostaglandins, May 1978, vol. 15, No. 5, pp. 737-750.

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