MR method and apparatus employing magnetization transfer contras

Electricity: measuring and testing – Particle precession resonance – Using a nuclear resonance spectrometer system

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1286531, G01V 300

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active

052706524

ABSTRACT:
A magnetic resonance and apparatus in which an examination zone is exposed, preferably repeatedly, with a sequence in which the same RF pulse is both selective to fat, for acting in a fat suppression scheme within the sequence and is configured for inducing substantial magnetization transfer contrast. Design parameters are given for a 1-2-1 binomial RF pulse and a 1-2-1-1-2-1double binomial RF pulse having a 0.degree. net flip angle at the Larmor frequency of water protons and a nominal 180.degree. net flip angle at the Larmor frequency of fat bound protons. The partial derivatives of the latter nominal flip angle with respect to chemical shift and with respect to RF amplitude are each zero. Each of these RF pulse designs is implemented by a pulse which is substantially rectangular in amplitude, but which has alternations of phase between 0.degree. and 180.degree. during its duration to form the sub-pulses. An illustrative imaging sequence incorporates this RF pulse for preparing the spin system n the examination zone prior to an at least partial tipping of longitudinal magnetization into the transverse plane by an RF excitation pulse.

REFERENCES:
patent: 5050609 (1991-09-01), Balaban et al.
"Three Dimensional Gadolinium-Enhanced MR Imaging of the Breast: Pulse Sequence with Fat Suppression and Magnetization Transfer Contrast" Radiology 1991, No. 181.
"Incidential Magnetization Transfer Contrast in Standard Multislice Imaging" Magnetic Resonance Imaging, vol. 8, pp. 417-422, 1990.
"Pulsed Magnetization Transfer Contrast" Book of Abstracts, Soc. of Magnetic Resonance in Medicine, 9th Ann. Meeting, 1990, p. 352.
"Magnetization Transfer Contrast (MTC) and Tissue Water Proton Relaxation in Vivo" Magnetic Resonance in Medicine 10, 135-144 (1989).

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