Process for preparing 5-substituted pyrrolo-[2,3-d]pyrimidines

Details Process for preparing 5-substituted pyrrolo-[2,3-d]pyrimidines Process for preparing 5-substituted pyrrolo-[2,3-d]pyrimidines

1996-01-31

1997-03-18

Grumbling, Matthew V.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

C07D48702

Patent

active

056124821

ABSTRACT:
Processes for preparing 5-substituted pyrrolo[2,3-d]pyrimidines which are useful as intermediates for the preparation of pyrrolo[2,3-d]pyrimidine antineoplastic agents or as antineoplastic agents themselves are provided.

REFERENCES:
patent: 4997838 (1991-03-01), Akimoto et al.
patent: 5235053 (1993-08-01), Barnett et al.
patent: 5278307 (1994-01-01), Barnett et al.
patent: 5403843 (1995-04-01), Akimoto et al.
patent: 5426187 (1995-06-01), Barnett et al.
Miwa, et al., J. Med. Chem., 34, 555-560 (1991).
Noell, C.W., et al., J. Heterocyclic Chem., 1, 34-41 (1964).
Kandasamy Ramasamy, et al., J. Chem. Soc. Chem. Commun. 560-562 (1989).
Secrist, J.A., et al., J. Org. Chem., 43, 3937-3941 (1978).
DeGraw, J. I., et al., J. Med. Chem., 25, 1227-1230 (1982).
Taylor, C. E., et al., J. Org. Chem.,55, 3222-3227 (1990).

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