Method of laser-induced tissue necrosis in carotenoid-containing

Surgery – Instruments – Light application

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606 3, 128898, A61B 1736

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053041704

ABSTRACT:
A method for treating dermatological organ disorders and skin lesions in a mammal through the use of directed, pulsed laser light is described.
The dermatological disorders are characterized by an increase in concentration of potential photodynamic chemical compounds like carotenoid compounds, and especially the carotenoid beta-carotene, compared to normal skin. Pulsed dye laser light of a time and duration specific for maximal absorption by a carotenoid compound like beta-carotene is directed at the regions of carotenoid accumulation within a skin disorder. Thermal coagulation necrosis of the carotenoid-accumulating skin region results, though thermal damage to surrounding tissue is limited in amount.

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