Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...
Patent
1998-12-10
2000-03-14
Berch, Mark L.
Organic compounds -- part of the class 532-570 series
Organic compounds
Nitrogen attached directly or indirectly to the purine ring...
544256, 544267, 544271, 544272, 544311, 544312, C07D47334, C07D47330, C07D47322, C07D23956
Patent
active
060374705
ABSTRACT:
The present invention comprises a method of synthesizing compounds of formula (I): wherein Z, R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.8 are as described herein; comprising the steps of.
REFERENCES:
Some New N-Methylpurines, Gertrude B. Elion, CIBA foundation Symp. Chem Biol. Purines, 1957, pp. 39-49.
Selective Type IV Phosphodiesterase Inhibitors as Antiasthmatic Agents. The Synthesis and Biological Activities of 3-(Cyclopentyloxy)-4-methoxybenzamides and Analogues, Michael J. Ashton, et al., Journal of Medicinal Chemistry, 1994, vol. 37, No. 11, pp. 1696-1703.
Synthesis of 3-Methylisoguanine [6-Amino-3-methylpurin-2(3H)-one], G.T. Rogers and T.L.B. Ulbricht, J. Chemical Soc.(C), 1971, pp. 2364-2366.
Synthesis of Potential Anticancer Agents. XIX. 2-Substituted N.sup.6 -Alkyladeninse, John A. Montgomery, Lee B. Holum and Thomas P. Johnston, The Kettering-Meyer Laboratory, Southern Research Institute, Aug. 5, 1959, vol. S. pp. 3963-3967.
Cavalla David J.
Chasin Mark
Hofer Peter
Berch Mark L.
Euro-Celtique S.A.
LandOfFree
Purine compounds having PDE IV inhibitory activity and methods o does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Purine compounds having PDE IV inhibitory activity and methods o, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Purine compounds having PDE IV inhibitory activity and methods o will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-170576