Process for producing optically active 1,3-butanediol by reducti

Details Process for producing optically active 1,3-butanediol by reducti Process for producing optically active 1,3-butanediol by reducti

1993-04-30

1995-05-09

Robinson, Douglas W.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing oxygen-containing organic compound

435280, 435822, 435911, C12P 718

Patent

active

054139228

ABSTRACT:
An optically active 1,3-butanediol can be produced by either (1) treating a mixture of 1,3-butanediol enantiomers with a microorganism, which has been optionally treated, capable of asymmetrically assimilating said mixture, or (2) preparing a microorganism, which has been optionally treated, capable of asymmetrically reducing 4-hydroxy-2-butanone, and collecting optically active 1,3-butanediol.

REFERENCES:
patent: 5219757 (1993-06-01), Matsuyama et al.
Christen M. et al., J. Chem. Soc. Chem. Commun 1988 pp. 264-266.
Chemical Abstracts, vol. 100, No. 100:21558m, p. 402 (1984).
Chemical Abstracts, vol. 27, No. 7 (1933).
Levene et al., J. Biol. Chem., 94, pp. 361-366, (1931).
Neuberg et al., Biochem. Z., 92, pp. 96-110 (1918).
Murakami et al., Bulletin of the Chemical Society of Japan, vol. 53, No. 5, pp. 1356-1360, (1980).

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