Hydroxylation of salicylic acid derivatives

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof

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424 91, C07C22716

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active

058409661

ABSTRACT:
The invention disclosed relates to the novel compound 5-amino tetrahydroxy benzoic acid and derivatives thereof, e.g. pharmaceutically acceptable acid addition salts, to a process for the preparation thereof which involves reacting 5-amino salicylic acid with hydroxyl radical, and to a method of using 5-amino tetrahydroxy benzoic acid and derivatives thereof as a biomarker for the presence of hydroxyl radical in biological systems.

REFERENCES:
patent: 3931295 (1976-01-01), Massie
Dull et al, Biochem Pharm., vol. 36, #15, pp. 2467-2472, 1987.

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