Detecting reagent for antiplatelet antibody

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435 724, 435961, 436578, 436520, 436528, 436533, 436534, 436543, 436829, G01N 33543, G01N 33544, G01N 33546, G01N 33555

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active

052886107

ABSTRACT:
A detecting reagent for an antiplatelet antibody, comprises a carrier particle, and a platelet antigen component immobilized on a surface of the carrier particle. The reagent particles do not agglutinate with each other, contrary to the platelets subjected to natural agglutination, probably because the platelet membrane antigen component immobilized on the carrier particle is solubilized in advance.

REFERENCES:
patent: 4959308 (1990-09-01), Ogden
patent: 5110726 (1992-05-01), Ogden
I. M. Roitt, Essential Immunology, 5th Edition, Blackwell Scientific Publications, Oxford, UK, 1984, pp. 159-161.
W. J. Herbert, in D. M. Weir (Ed.), Handbook of Experimental Immunology, Third Edition, Blackwell Scientific Publications, Oxford, 1978, Chapter 20.

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