Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Primate cell – per se
Patent
1997-05-14
1998-11-24
Stanton, Brian R.
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
Primate cell, per se
424 931, 435325, 435326, A01N 6300, C12N 506, C12N 508
Patent
active
058405801
ABSTRACT:
One or more population of cells enriched for human hematopoietic stem cells is disclosed. HSC in this population of cells are capable of limited self-renewal and are capable of differentiating into all elements of the hematopoietic system. This population of cells has the phenotype of CD34.sup.+ /CD38.sup.- and more preferably CD34.sup.+ /CD38.sup.- /HLA-DR.sup.+. Cells within this population have been found to express CD13, CD33 and CD71. Hematopoietic stem cells can be used in a number of therapies, including autologous transplantation and in gene therapy.
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Huang Shiang
Loken Michael R.
Lund-Johansen Fridtjof
Olweus Johanna
Terstappen Leon W.
Becton Dickinson and Company
Capello Susan A.
Ronning, Jr. Royal N.
Stanton Brian R.
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