Treatment of cellulite with retinoids

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...

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514381, 514415, 514448, 514461, 514532, 514622, 514725, A61K 3120

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active

050514490

ABSTRACT:
A method for retarding and reversing cellulite comprises topically applying to human skin a retinoid in an amount and for a period of time effective to retard or reverse cellulite where said amount is insufficient to be excessively irritating. The method preferably uses retinoic acid in an emollient vehicle.

REFERENCES:
patent: 3729568 (1969-09-01), Kligman
patent: 4288633 (1981-09-01), Koulbams et al.
patent: 4603146 (1986-07-01), Kligman
patent: 4877805 (1989-10-01), Kligman
patent: 4888342 (1989-12-01), Kligman
Pawson, B. A. et al., "Retinoids at the Threshold: Their Biological Significance and Therapeutic Potential," Journal of Medicinal Chemistry 25:1269-1277 (1982)-(Chemical Abstract).
Thomas, J. R. et al., "The Therapeutic Uses of Topical Vitamin A Acid," Journal of American Academy of Dermatology 4:505-516 (1981).

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