Pyrrolidine derivatives as anti-amnesia agents

Details Pyrrolidine derivatives as anti-amnesia agents Pyrrolidine derivatives as anti-amnesia agents

1989-09-18

1991-09-24

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548518, 548540, 548539, 548572, 548336, 548468, 514422, 514423, 514428, 514414, A61K 31415, C07D20700, C07D40300, C07D20902

Patent

active

050514440

ABSTRACT:
The present invention relates to pyrrolidine derivatives of the formula ##STR1## wherein R.sup.1 and R.sup.2 are defined as herein. The compounds are useful as anti-amnestic agent.

REFERENCES:
patent: 4774255 (1988-09-01), Black et al.
Science, 211, pp. 601,603 (1981); Weingartner et al.
Brain Research, 157, pp. 414-417 (1978); Bohus, et al.
Journal of Biochemstry, 94 pp. 1179-1190 (1983); Yoshimoto et al.
Biochemistry, 16, pp. 2942-2948 (1977); Yoshimoto et al.
Journal of Neurochemistry, 41, pp. 69-75 (1983); Wilk et al.

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