Transdermal administration of buprenorphine

Details Transdermal administration of buprenorphine Transdermal administration of buprenorphine

1990-06-20

1991-12-03

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Web, sheet or filament bases; compositions of bandages; or...

424448, 514947, A61F 1300

Patent

active

050699091

ABSTRACT:
Method and laminated composite for administering buprenorphine transdermally to treat pain. The composite comprises an impermeable backing layer and a reservoir layer containing buprenorphine and optionally a permeation enhancer combined with a pressure-sensitive adhesive with the amounts of buprenorphine and optional enhancer being sufficient to cause the buprenorphine to pass through the skin at a rate in excess of about 0.05 mcg/cm.sup.2 /hr.

REFERENCES:
patent: 3433791 (1969-03-01), Bentley
patent: 4626539 (1986-12-01), Aungst et al.
patent: 4806341 (1989-02-01), Chien et al.
patent: 4956171 (1990-09-01), Chang
Adriensen, H. et al., Acta. Anaesthesia Belg. (1985) 36:33-40.
Bickel, W. K. et al., Chem. Pharmacol. Ther. (1990) 43:72-78.
Bullingham, R. et al., Clin. Pharmacol. Ther. (1980) 28:667-72.
Bullingham, R. et al., Clin. Pharmacol. (1983) 8:332-43.
Bullingham, R. et al., British Clin. Pharmacol. (1982) 13:665-73.
Fudala, P. J. et al., Clin. Pharmacol Ther. (1990) 47:4:525-534.
Heel, R. C. et al., "Buprenorphine: A Review of Its Pharmacological Properties and Therapeutic Efficacy", Drugs (1979) 17:81-110.
O'Sullivan, G. H. et al., Anaesthesia (1983) 38:977-84.
Ostrowski, M. J. et al., British J. Clin. Pharmacol. (1979) 33:587-90.
Rosana, C. et al., Clin. Ther. (1982) 5:61-8.
Martindale: The Extra Pharmacopeia, Entry 6209-w (Buprenorphine Hydrochloride), London: The Pharmaceutical Press, 1989.
Physician's Desk Reference, 43rd Edition, pp. 1476-1477 ("Buprenex") (1989).

Affiliated with

Also associated with

Rating

Transdermal administration of buprenorphine does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Transdermal administration of buprenorphine, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Transdermal administration of buprenorphine will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1695953