Sterodial liposomes

Details Sterodial liposomes Sterodial liposomes

1991-09-12

1994-02-22

Lovering, Richard D.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

264 41, 264 46, 424 71, 424 121, 4284022, 436829, 514 78, 514167, 514887, 514967, A61K 9127, A61K 9133, A61K 3722

Patent

active

052884996

ABSTRACT:
Methods and compositions are described for the preparation of bioactive agents entrapped in lipid vesicles the bilayers of which comprise a salt form of an organic acid derivative of a sterol, such as the tris-salt form of a sterol hemisuccinate, and to compositions comprising a mixture of tris(hydroxymethyl)aminomethane salt of cholesteryl hemisuccinate with either an antifungal compound or a peptide. These compositions have various applications in vivo.

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