Synthesis of stable water-soluble chemiluminescent 1,2-dioxetane

Details Synthesis of stable water-soluble chemiluminescent 1,2-dioxetane Synthesis of stable water-soluble chemiluminescent 1,2-dioxetane

1991-04-03

1993-07-06

Raymond, Richard L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Phosphorus esters

556405, 549221, 549332, 549510, 558109, 558187, C07F 940

Patent

active

052255840

ABSTRACT:
A novel synthesis of compounds having the formula: ##STR1## wherein T is a stabilizing spiro-linked polycycloalkylidene group, R.sup.3 is a C.sub.1 -C.sub.20 alkyl, aralkyl or heteroatom containing group, Y is an aromatic fluorescent chromophore, and Z is a cleavable group which, when cleaved, induces decomposition of the dioxetane ring and emission of optically detectable light, is disclosed. A tertiary phosphorous acid alkyl ester of the formula:

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