Process for activating a polymer surface for covalent bonding fo

Details Process for activating a polymer surface for covalent bonding fo Process for activating a polymer surface for covalent bonding fo

1991-02-14

1992-07-28

Welsh, Maurice J.

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Mixing of two or more solid polymers; mixing of solid...

523112, 525433, 525452, 525454, 4284231, 530352, 530380, 427 2, 427384, C08H 100

Patent

active

051341921

ABSTRACT:
A dicarbonyl halide preferably a straight-chain-alkyl dicarbonyl dihalide, may be used to activate a substrate surface of preferably polyurethane or polyamide. Optionally, an amine-end blocked polymer may be reacted with the resulting activated surface by reaction between amine and dicarbonyl halide groups. Then, a material to be covalently bonded to said surface, such as heparin, may be reacted with free amine groups bonded to the surface by a carbodiimide process or the like.

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Article by Gerardus Henricus Maria Engbers, entitled: Development of Heparinized Materials With an Improved Blood Compatibility, Jun. 28, 1990, pp. 147-190.

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