Use of a statin derivative in the treatment of eye complaints

Details Use of a statin derivative in the treatment of eye complaints Use of a statin derivative in the treatment of eye complaints

1990-06-04

1992-07-28

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514913, A61K 3700

Patent

active

051341247

ABSTRACT:
The invention relates to the use of N-(3-pyridylpropionyl)phenylalanylhistidyl (cyclohexyl)statyl-N-(1,3-dihydroxy-2-methylpropyl)isoleucinamide, which has the formula ##STR1## in which: Phe is the (L)-phenylalanine residue, His is the (L)-histidine residue, Ile is the (L)-isoleucine residue and (cyclohexyl)Sta is the cyclohexylstatin residue, i.e. the (3S, 4S)-4-amino-5-cyclohexyl-3-hydroxypentanoic acid residue, for the preparation of drugs useful in the treatment of eye complaints. Application: treatment of eye complaints.

REFERENCES:
patent: 4906613 (1990-03-01), Watkins
Giardina et al., J. Ocular Pharmacology, 6(2), 1990, p. 75.

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