Certain aryl substituted pyrrolopyrazines; a new class of GABA b

Details Certain aryl substituted pyrrolopyrazines; a new class of GABA b Certain aryl substituted pyrrolopyrazines; a new class of GABA b

Filed on

1997-09-16

Date issued

1999-06-08

Examiner

Shah, Mukund J.

Patent Class

Organic compounds -- part of the class 532-570 series

SubClass

Organic compounds

SubSubClass

Nitrogen attached directly or indirectly to the purine ring...

Other Related Categories

C07D47100, C07D48700, C07D49100, C07D49500

Type

Patent

Status

active

Patent number

059105909

Description

ABSTRACT:
Compounds of the formula ##STR1## wherein R' and R" are independently hydrogen or lower alkoxy having 1-6 carbon atoms; and R'" is halogen are disclosed. These compounds are highly selective agonists, antagonists or inverse agonists for GABAa brain receptors and are useful in the diagnosis and treatment of anxiety, sleep and seizure disorders, overdose with benzodiazepine type drugs, and enhancement of alertness.

REFERENCES:
patent: 5286860 (1994-02-01), Blum et al.
patent: 5606059 (1997-02-01), Blum et al.
patent: 5668283 (1997-09-01), Blum et al.

Affiliated with

Also associated with

Rating

Certain aryl substituted pyrrolopyrazines; a new class of GABA b does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Certain aryl substituted pyrrolopyrazines; a new class of GABA b, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Certain aryl substituted pyrrolopyrazines; a new class of GABA b will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1684056