Method for screening for the presence of a genetic defect associ

Details Method for screening for the presence of a genetic defect associ Method for screening for the presence of a genetic defect associ

1996-06-05

1999-06-08

Loring, Susan A.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Blood proteins or globulins, e.g., proteoglycans, platelet...

5303879, 53038885, 5303893, 530381, C07K 1600, A61K 3514

Patent

active

059105763

ABSTRACT:
Method for screening for the presence of a genetic defect associated with thrombosis and/or poor anticoagulant response to activated protein C (APC). The method is directed at detecting one or more mutations at one or more of the cleavage and/or binding sites for APC of Factor V and/or Factor Va or at Factor VIII and/or Factor VIIIa at either nucleic acid or protein level or both.

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