Surgery – Means for introducing or removing material from body for... – Treating material introduced into or removed from body...
Patent
1993-03-23
1994-04-19
Grieb, William H.
Surgery
Means for introducing or removing material from body for...
Treating material introduced into or removed from body...
604 58, 12820014, 7386322, 73 2805, A61M 3100, A61M 1100
Patent
active
053041259
ABSTRACT:
An apparatus for administering an aerosol of a solid particulate medicament (e.g., amiloride) to the lungs of a patient is disclosed. The apparatus comprises a solid particulate medicament aerosol generator and an impactor assembly for removing large particles of medicament from the aerosol produced by the aerosol generator. The impactor assembly comprises an enclosed chamber having an inlet opening and an outlet opening formed on opposite sides thereof. The aerosol generator is connected to the inlet opening. A first impactor plate is positioned in the chamber, with the first impactor plate adjacent the inlet opening. The first impactor plate has an uninterrupted primary impaction surface formed thereon, with the primary impaction surface substantially axially aligned with the inlet opening and having a diameter not less than the inlet opening. The first impactor plate has at least one exhaust opening formed therein in fluid communication with the outlet opening. An aerosol of solid particulate medicament is passed from the aerosol generator through the impactor assembly where large particles are removed, and then to the subject for inhalation.
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Grieb William H.
Passaniti Sebastiano
The University of North Carolina
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