Synthesis of oligonucleotide arrays using photocleavable protect

Details Synthesis of oligonucleotide arrays using photocleavable protect Synthesis of oligonucleotide arrays using photocleavable protect

1996-04-10

2000-02-08

Wilson, James O.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 2531, 536 2532, 536 2533, 536 2534, 536 256, 536124, 435 6, 435 792, 435 794, 435 795, 436518, 436527, 436528, 436807, C07H 2100

Patent

active

060229632

ABSTRACT:
Novel compounds are provided which are useful as linking groups in chemical synthesis, preferably in the solid phase synthesis of oligonucleotides and polypeptides. These compounds are generally photolabile and comprise protecting groups which can be removed by photolysis to unmask a reactive group. The protecting group has the general formula Ar--C(R.sub.1)(R.sub.2)--O--C(O)-- wherein:

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