Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1998-04-29
2000-02-08
Burke, Julie
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 911, 536 231, 536 243, 536 2431, 536 2433, C12Q 168, C07H 2104, C12N 1511
Patent
active
060226927
ABSTRACT:
A new family of tumor rejection antigen precursors, and the nucleic acid molecules which code for them, are disclosed. These tumor rejection antigen precursors are referred to as DAGE tumor rejection antigen precursors, and the nucleic acid molecules which code for them are referred to as GAGE coding molecules. Various diagnostic and therapeutic uses of the coding sequences and the tumor rejection antigens, and their precursor molecules are described.
REFERENCES:
patent: 5342774 (1994-08-01), Boon et al.
patent: 5405940 (1995-04-01), Boon et al.
patent: 5530096 (1996-06-01), Wolfel et al.
patent: 5554506 (1996-09-01), van der Bruggen
patent: 5554724 (1996-09-01), Melief et al.
patent: 5558995 (1996-09-01), van der Bruggen
patent: 5587289 (1996-12-01), Lurquin et al.
Coulie et al, "A New Gene Coding For A Differentiation Antigen Recognized By Autologous Cytolytic T. Lymphocytes", J. Exp. Med. 180: 35-42 (7-94).
Engelhardt, "Structure of Peptides Associated With Class I and Class II Molecules", Ann. Rev. Immunol 12: 181-207 (1994).
Falk et al., "Allele specific peptide ligand motifs of HLA-C molecules", Proc. Natl. Acad. Sci. USA 90: 12005-12009 (Dec. 1993).
Van der Bruggen et al., "A Gene Encoding An Antigen Recognized By Cytolytic T Lymphocytes on a Human Melanoma", Science 254: 1643-1647 (1991).
Rotzschke, et al "Isolated and analysis of naturally processed viral peptides as recognized by cytolytic T cells", Nature 348: 252-254 (11-15-1990).
Bjorkman et al., "The foreign antigen binding site and T cell recognition of class I histocompatibility antigens", Nature 329: 512-518 (Oct. 8, 1997).
Zemmour et al., "HLA Class I nucleotide sequences, 1992", Immunogenetics 37: 239-259 (1993).
Rupert et al., "Prominent Role of Secondary Anchor Residues In Peptide Binding to HLA-A2.1 Molecules", Cell 74: 929-937 (Oct. 9, 1993).
Falk et al., "Allele specific peptide ligand motifs of HLA-C molecules", Proc. Natl. Acad. Sci. USA 90: 12005-12009 (Dec. 1993).
Traversari et al., "A Nonapeptide Encoded by Human Gene MAGE-1 Is Recognized on HLA-A1 By Cytolytic T Lymphocytes, Directed Against Tumor Antigen MZ2-E", J. Exp. Med. 176: 1453-1457 (Nov. 1992).
Ikeda, et al., "Characterization of an Antigen That Is Recognized On a Melanoma Showing PartialHLA Loss By CTL Expressing an NK Inhibitory Receptor," Immunity 6:199-208 (1997).
Robbins, et al., "Recognition of Tyrosinase By Tumor Infiltrating Lymphocytes From a Patient Responding to Immunotherapy" Canc. Res 54:3124-3126 (1994).
Boon-Falleur Thierry
Coulie Pierre
Ikeda Hideyuki
Burke Julie
Ludwig Institute for Cancer Research
LandOfFree
Method for screening for possible presence of cancer does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for screening for possible presence of cancer, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for screening for possible presence of cancer will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1679902