Novel process of producing phenyl or substituted phenylalkylamin

Details Novel process of producing phenyl or substituted phenylalkylamin Novel process of producing phenyl or substituted phenylalkylamin

1989-06-12

1990-08-21

Lone, Werren B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

564305, 564306, 564307, 568715, 568840, 568812, C07B 5700

Patent

active

049507915

ABSTRACT:
A process for producing the optically pure (+)- or (-) isomer of a phenyl- or substituted- phenylalkanolamine compounds having pharmacologic activity without the need for resolution processes and novel intermediates useful in the process including optically pure haloalcohols are provided.

REFERENCES:
patent: 4018895 (1977-04-01), Molloy et al.
patent: 4416827 (1983-11-01), Bethge et al.
patent: 4806690 (1989-02-01), Bowman
Pohland et al., "J. Amer. Chem. Soc." vol. 75 (1953) 4458-4461.
Brown, "J. Org. Chem.", vol. 50, (1985) 5446.

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